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| Lemos-Pinto,M.M.P.; Cadena,M.; Santos,N.; Fernandes,T.S.; Borges,E.; Amaral,A.. |
| Biological dosimetry (biodosimetry) is based on the investigation of radiation-induced biological effects (biomarkers), mainly dicentric chromosomes, in order to correlate them with radiation dose. To interpret the dicentric score in terms of absorbed dose, a calibration curve is needed. Each curve should be constructed with respect to basic physical parameters, such as the type of ionizing radiation characterized by low or high linear energy transfer (LET) and dose rate. This study was designed to obtain dose calibration curves by scoring of dicentric chromosomes in peripheral blood lymphocytes irradiated in vitro with a 6 MV electron linear accelerator (Mevatron M, Siemens, USA). Two software programs, CABAS (Chromosomal Aberration Calculation Software)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dicentrics; Calibration curves; Linear accelerator; CABAS; Dose Estimate. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001000008 |
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| Wenning,M.R.S.C.; Kimura,E.M.; Costa,F.F.; Saad,S.T.O.; Gervásio,S.; de Jorge,S.B.; Borges,E.; Silva,N.M.; Sonati,M.F.. |
| Seven unrelated patients with hemoglobin (Hb) H disease and 27 individuals with alpha-chain structural alterations were studied to identify the alpha-globin gene mutations present in the population of Southeast Brazil. The -alpha3.7, --MED and -(alpha)20.5 deletions were investigated by PCR, whereas non-deletional alpha-thalassemia (alphaHphalpha, alphaNcoIalpha, <FONT FACE="Symbol">aa</FONT>NcoI, alphaIcalpha and alphaTSaudialpha) was screened with restriction enzymes and by nested PCR. Structural alterations were identified by direct DNA sequencing. Of the seven patients with Hb H disease, all of Italian descent, two had the -(alpha)20.5/-alpha3.7 genotype, one had the --MED/-alpha3.7 genotype, one had the --MED/alphaHphalpha genotype and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alpha-globin genes; Alpha-globin structural variants; Alpha-thalassemia; Hemoglobin H; Hb H disease; Hemoglobin variants; Hemoglobinopathies. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000900008 |
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| Borges,E.; Wenning,M.R.S.C.; Kimura,E.M.; Gervásio,S.A.; Costa,F.F.; Sonati,M.F.. |
| In order to determine the contribution of alpha-thalassemia to microcytosis and hypochromia, 339 adult outpatients seen at Unicamp University Hospital (with the exception of the Clinical Hematology outpatient clinics), who showed normal hemoglobin (Hb) levels and reduced mean corpuscular volume and mean corpuscular hemoglobin, were analyzed. Ninety-eight were Blacks (28.9%) and 241 were Caucasians (71.1%). In all cases, Hb A2 and F levels were either normal or low. The most common deletional and nondeletional forms of alpha-thalassemia [-alpha3.7, -alpha4.2, --MED, -(alpha)20.5, alphaHphIalpha, alphaNcoIalpha, <FONT FACE="Symbol">aa</FONT>NcoI and alphaTSAUDI] were investigated by PCR and restriction enzyme analyses. A total of 169 individuals... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alpha-thalassemia; Microcytosis; Hypochromia; Hemoglobinopathies; Brazilian population. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600009 |
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| Borges,E.; Libardi,P. L.. |
| Um dos principais fatores que tornam necessário conhecer o movimento de solutos e os processos que determinam a interação destes com o solo é o problema da poluição do lençol freático. A percolação profunda de produtos químicos aplicados na superfície do solo, juntamente com observações em laboratório da diminuição na concentração de solutos em uma solução que atravessa o solo, levou os pesquisadores a considerar a água (ou solução) no solo em duas fases: uma móvel e outra imóvel. Neste trabalho, a umidade volumétrica na fase móvel (θm) da solução foi determinada para um solo não saturado no campo, utilizando duas concentrações de solução de KCl (0,1 e 0,05 mol L-1). No experimento, foram montadas três parcelas no solo da área experimental do Departamento... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Teor móvel da solução; KCl; Infiltração. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-06832002000200001 |
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